J00-J99 Diseases of the respiratory system
One study in Diseases of the respiratory system is accessible to registered UDBN website users.
UDBN partners:
Prof William Cookson (Imperial College London)
Dr Miriam Moffatt (Imperial College London)
See also Eczema family collection 2000.
Asthma and eczema are the most common diseases of childhood and are enormously expensive to treat. These diseases have strong genetic origins.
Gene discovery programs and candidate gene investigations are greatly limited by the availability of families to study.
This proposal will create a national collection of 1000 nuclear families with severe allergic disease. Five hundred nuclear families will be identified through a proband with severe atopic asthma and 500 nuclear families will be identified through a proband with severe atopic eczma.
Detailed studies of phenotype will be made according to internationally recognised criteria. DNA and phenotypic information from the families will act as a centralised resource to aid gene identification for the disorders within the United Kingdom.
To access individual data and samples, first register.
